Anti-HIV drug could reduce HIV in the Latino American community

drugFrom the Latin Post

When ingested daily, PrEP becomes present in the bloodstream and wards off the spread of HIV. The CDC reiterates the importance of taking the pill EVERY day. For those who take the medicines as directed, the risk of getting HIV infection plummets, up to 92 percent lower. However, failing to ingest the pill daily could mean an insufficient amount medicine in the body, and PrEP isn’t guaranteed to block the virus.

“I feel that it’s a great breakthrough in the fight against HIV. I know that we have public health strategy if we don’t drop the ball, as we have in many instances in the past,” Gustavo Morales, Director of Access to Care Services at the Latino Commission on AIDS, said to Latin Post. “Specifically what I mean by this is PrEP cannot be seen as the sole strategy, and it requires a counseling process, such as biomedical intervention that does require peer, hand-to-hand social support. Because, PrEP without adherence, without understanding the facts behind it, without risk awareness, without a conversation, is not effective.”

Read the full article.

Can HIV accelerate age-related conditions?

From MedicalExpress.com

To answer that question, researchers at the UCLA AIDS Institute and Center for AIDS Research and the Multicenter AIDS Cohort Study investigated whether the virus induces age-associatedepigenetic changes—that is, changes to the DNA that in turn lead to changes in expression of gene levels without changing the inherited genetic code. These changes affect biological processes and can be brought on by environmental factors or by the aging process itself.

In a study published online in the peer-reviewed journal PLOS ONE, the researchers suggest that HIV itself accelerates these aging related changes by more than 14 years.

“While we were surprised by the number of epigenetic changes that were significantly associated with both aging and HIV-infection, we were most surprised that the data suggests HIV-infection can accelerate aging-related epigenetic changes by 13.7 to 14.7 years,” said Beth Jamieson, professor of medicine in the division of hematology/oncology at the David Geffen School of Medicine at UCLA and one of the study’s senior authors. “This number is in line with both anecdotal and published data suggesting that treated HIV-infected adults can develop the diseases of aging mentioned above, approximately a decade earlier than their uninfected peers.”

Read the full article.

Advocate.com: 11 bad habits killing LGBT people

From the Advocate.com

ThinkstockPhotos-466033241X633We’re in the midst of LGBT Health Month, a time to take stock of the many health issues specific to our community. While we have plenty of people trying to do harm to us because of our sexual orientation or gender identity, we often don’t do ourselves any favors when it comes to self care. Here are the bad habits we should have given up last century.

New study shows gay and bi men twice as likely to get skin cancer

From USA Today

Gay and bisexual men in the United States are twice as likely as heterosexual men to get skin cancer, a new study shows.

One likely reason: Gay and bisexual men are three times more likely to engage in indoor tanning, according to the study to be presented Friday in San Francisco at a meeting of the American Academy of Dermatology.

The study suggests that anti-tanning messages, most often aimed at young women, need to be broader, says researcher Sarah Arron, an associate professor of dermatology at the University of California, San Francisco. “The primary reason that men and women engage in indoor tanning is because of the cultural association of tanning with a healthy look and overall attractiveness,” Arron says. “We need to dispel the myth of the healthy tan.”

Tanning, whether in the sun or in a tanning bed, can cause skin cancer, including melanoma, the most dangerous kind, according to the U.S. Surgeon General’s office.

Free AIDSINFO drug app: HIV-Related drug information for health care providers and consumers

Healthcare providers and consumers need HIV-related drug information and, increasingly, they depend on mobile devices to access that information. AIDSinfo is meeting both needs with the release of the AIDSinfo Drug App. Using data from theAIDSinfo Drug Database, the drug app provides information on more than 100 HIV-related Food and Drug Administration (FDA)-approved and investigational drugs. The AIDSinfo Drug App—provided free from the National Library of Medicine at the National Institutes of Health—is available for iOS and Android devices.

The information on the AIDSinfo Drug App, offered in English and Spanish, is tailored to meet the needs of both healthcare providers and consumers. The app works offline, ensuring that healthcare providers and consumers can access vital drug information anywhere—even in healthcare facilities that may not have an Internet connection.

The AIDSinfo Drug App pulls FDA labels from Daily Med for approved HIV-related drugs. The app also integrates information on drug nomenclature and chemical structure from ChemIDplus. Information from the labels is condensed in easy-to-understand summaries in English and Spanish for consumers.

Users can also access information on HIV-related drugs under investigation via the AIDSinfo Drug App. The investigational drug summaries, which are developed from the latest clinical trial results, are tailored by audience: technical, more detailed summaries for healthcare providers and less complex summaries in English and Spanish for consumers.

Users can also personalize the AIDSinfo Drug App. According to their needs, users can set pill reminders, bookmark drugs, or add personal notes:

  • Set pill reminders: Medication adherence is crucial to successful HIV treatment, and the app’s medication reminder can help those taking HIV medicines stay on schedule. Choosing from a menu of alarms, app users can set pill reminders for any time of the day and any day of the week.
  • Bookmark drugs: Busy users can bookmark frequently referenced drugs. No more searching for the same drugs again and again.
  • Add notes: App users can also customize drugs with personal notes. For example, patients can add notes during medical visits; healthcare providers can add relevant information useful at the point of care.

Stay tuned as AIDSinfo updates the app with additional features. Visit AIDSinfo to download the drug app to your iOS or Android device. And keep us posted on your experience with the app. We welcome your questions and comments at ContactUs@aidsinfo.nih.gov.

Diagnoses of HIV Infection in the United States 2013 is now available online

map2From the CDC

The Centers for Disease Control and Prevention’s (CDC) annual HIV Surveillance Report titledDiagnoses of HIV Infection in the United States and Dependent Areas, 2013, is now available online [PDF 2.9MB]. The report summarizes information about diagnosed HIV infection from 2009 to 2013 representative of all 50 states, the District of Columbia, and six U.S. dependent areas. Overall, HIV diagnosis rates remain stable yet disparities persist among some groups.

The report shows that the annual rate of diagnosis in the United States remained stable with 15.0 per 100,000 in 2013 compared to 15.3 per 100,000 in 2009.

Despite this, disparities persist—and in some cases—rates have increased among certain groups. As evidenced by this report and other previously released data, gay, bisexual, and other men who have sex with men (MSM); young adults; and racial and ethnic minorities continue to bear the disproportionate burden of HIV…

Continue reading.

HIV health advocates reach gay men at risk on cell phone apps

images (1)From the Washington Blade

Hook-up apps on smartphones continue to be an avenue for HIV health advocates to reach gay men at risk, Bloomberg reports.

Citing surging rates of new infections in gay and bi men 24 or younger, the San Francisco AIDS Foundation and the CDC coordinated an online campaign last month with several dating services to promote testing. The messages, which were donated by the app companies, were seen by 19 million users and more than 30,000 clicked through for more information, Hecht said.

Hornet and Jack’d are among dating apps that have undertaken their own awareness campaigns, deploying them in regions with less public discussion about the virus that causes AIDS. Last year Hornet teamed with a local non-profit in the Philippines to send messages to 94,000 users about testing services, with links for online registration. More than 4,300 men responded, and 539 were HIV positive, said Sean Howell, founder and chief executive officer of the San Francisco-based company.

“Gay men are always on their phone, looking for other gay men,” said Howell, 34, who created Hornet after he realized how much time his friends spent online. “We have 4 million users worldwide who are at the highest risk for HIV and we have their attention.”

 

 

February 7 is National Black HIV/AIDS Awareness Day

From AIDS.gov

Like so many Americans, I have seen the tragedy first hand, of friends lost to HIV/ AIDS. I’ve also seen the hope of those living with HIV as we continue to work toward an AIDS free generation.

Each February 7th, we mark National Black HIV/AIDS Awareness Day (NBHAAD). It’s an opportunity for all of us to honor the memory of those we’ve lost, and to call attention to the fact that HIV continues to disproportionately affect African American men, women, and youth.

The numbers are startling: African Americans represent only 14 percent of the U.S. population, but account for almost half of all new HIV infections in the United States per year, as well as more than one-third of all people living with HIV in our nation.

NBHAAD Banner

This year’s NBHAAD theme, “I Am My Brother’s/Sister’s Keeper: Fight HIV/AIDS” challenges all of us to work to eliminate these unacceptable health disparities by ramping up our HIV prevention efforts, encouraging individuals to get tested, and helping those who are living with HIV to access the life-saving medical treatment they need.

One of the ways the Department of Health and Human Services is responding to this charge is by launching a new four-year demonstration project funded through the Secretary’s Minority AIDS Initiative to address HIV disparities among men who have sex with men (MSM), including men of color.

We are focusing on HIV disparities among MSM, including MSM of color, because black gay and bisexual men—particularly young men—remain the population most heavily affected by HIV in the U.S. Young black MSM account for more new infections (4,800 in 2010) than any other subgroup of MSM by race/ethnicity and age. These shocking figures demand that we take action.

The cross-agency demonstration project will support community-based models in strengthening HIV prevention efforts, addressing gaps in care for those living with HIV, and helping meet the health care needs of MSM, including MSM of color. More specifically, the funding will support state and local health departments in providing MSM of color, and other MSM, with the health and social services they need to live healthy lives free of HIV infection. For those already infected, the funding will support community-based services that help MSM of color, and other MSM, get diagnosed and linked to the right care—including substance abuse and mental health treatment as well as necessary social services, like stable housing. Helping people access and remain in HIV care is good medicine and important to our public health—since it lowers individuals’ risk of passing HIV to others.

We all have a role to play in working toward an AIDS free generation. Education and understanding prevention and treatment of HIV is important. And HIV testing is also critical as we continue to tackle this disease. One thing we can all do is speak out – speak out against HIV stigma whenever and wherever you encounter it. Stigma and shame continue to prevent too many people from seeking testing and getting the health care they need to live healthy, active lives.

Read more about HIV among African Americans and efforts to prevent and treat this disease at CDC.gov.

Study shows “it get better,” but…

A new study released in the Journal of Adolescent Health looked at the lives of 231 LGBTQ adolescents to see if it really does get better–referencing the It Gets Better campaign launched by activist Dan Savage. After following the youth for 3.5 years, researchers at Northwest University in Chicago found that, technically, yes, “it gets better.” But the findings also suggested a more complex set of mental health issues at play for LGBTQ youth. In short, things don’t automatically get better. Early experiences of victimization were shown to have a lasting impact on later psychological functioning. As a result, researchers went on to suggest the need for interventions which decrease stigma and victimization at an early age.

You can read more about the study on  Reuters Health.

Study finds H.I.V. drugs priced out of reach

From the New York Times

Drugs to treat H.I.V. and AIDS are being priced out of reach for many patients enrolled in insurance plans through the new health care exchanges, despite warnings that such practices are illegal under the Obama administration’s health care law, according to a new analysis by Harvard researchers.

The study, to be published on Wednesday in an article in The New England Journal of Medicine, looked at 48 health plans in 12 states and found that a quarter of the plans showed evidence of what researchers called “adverse tiering,” or placing all of the drugs used to treat H.I.V. in a specialty tier where consumers are required to pay at least 30 percent of the cost of the drug.

The financial impact can be drastic, the researchers found: A patient taking a common H.I.V. treatment, Atripla, would pay about $3,000 more a year in a restrictive plan compared with someone enrolled in a more generous plan, even after accounting for the fact that the more restrictive plans tended to charge lower monthly premiums.

“That’s really a large cost difference, and really is a very significant financial constraint for those with chronic conditions, particularly H.I.V.,” said Douglas B. Jacobs, the lead author of the study, who is pursuing degrees in public health at the Harvard T. H. Chan School of Public Health and medicine at the University of California, San Francisco.

Continue reading on The New York Times.

10 questions to ask yourself before you begin HIV treatment

puzzle man_white backgroundFrom thebody.com

An HIV diagnosis comes with its very own set of questions to ask yourself and decisions to make. Among the biggest is: When should you start treatment? It’s a Russian nesting doll of a decision, with many other questions tucked inside. Here, in no particular order, are 10 of the most important questions to ask yourself before you begin taking HIV medications.

Get Started

Mental health issues put gay and bi men at increased risk for HIV

(Reuters Health) – Gay and bisexual men are at increased risk of acquiring the virus that leads to AIDS if they have mental health problems, according to a new study. What’s more, their risk of acquiring HIV increases with the number of mental health factors they report, researchers found. Past studies have found that mental disorders, ranging from depression to substance abuse, are often seen among men with HIV, but “nothing about whether these factors predict HIV risk behaviors or becoming infected with HIV,” said study leader Matthew Mimiaga, from Harvard Medical School and Massachusetts General Hospital in Boston.

The Centers for Disease Control and Prevention (CDC) estimates that some 1.1 million people in the U.S. are living with HIV. About one case in six is undiagnosed. While the CDC says only about 4 percent of U.S. males have sex with other men, they represent about two-thirds of the country’s new infections. Additionally, it’s known that the lesbian, gay, bisexual and transgender (LGBT) community also suffers from an increased burden of mental health problems.

When two health conditions tend to occur together in one population, researchers call them “syndemic.” For the new study in the Journal of Acquired Immune Deficiency Syndromes, the researchers looked at how five conditions – depression, alcohol abuse, stimulant use, multi-drug abuse and exposure to childhood sexual violence – affect men’s risk of acquiring HIV. They analyzed data on 4,295 men who reported having sex with men within the previous year. The participants were asked about depressive symptoms, heavy alcohol and drug use and childhood sexual abuse.

Read more

 

CDC annual STD surveillance report: MSM bear a disproportionate burden

From the EdgeMediaNetwork

While anyone can become infected with an STD, certain groups, including young people and gay and bisexual men, are at greatest risk. Gonorrhea and chlamydia primarily affect young people. While surveillance data show signs of potential progress in reducing chlamydia and gonorrhea among young people aged 15-24, both the numbers and rates of reported cases of these two diseases continue to be highest in this group compared to other age groups. 

Both young men and young women are heavily affected by STDs, but young women face the most serious long-term health consequences. It is estimated that undiagnosed STDs cause 24,000 women to become infertile each year. The other group facing the burden of STDs are men who have sex with men (MSM). There has been a troubling rise in syphilis infections among gay, bisexual, and other MSM. Trend data show that MSM account for three quarters (75 percent) of all primary and secondary syphilis cases. 

Primary and secondary syphilis are the most infectious stages of the disease, and if not adequately treated, can lead to long-term infection, which can cause visual impairment and stroke. Syphilis infection can also place a person at increased risk for acquiring or transmitting HIV infection. In fact, available surveillance data indicate that an average of half of MSM with syphilis are also infected with HIV. 

Read the full article here.
Read the CDC report here.

US guidelines on “prevention with positives” now emphasize engagement with care, HIV treatment and social factors

From aidsmap.com

The American public health agency, the Centers for Disease Control and Prevention (CDC) has published new recommendations on the HIV prevention interventions and advice that should be offered to people who are HIV positive.

The CDC last issued guidelines on what is sometimes called ‘prevention with positives’ in 2003. Those guidelines ran to 24 pages and emphasised screening for behavioural risk factors and sexually transmitted infections, one-to-one prevention counselling and advice delivered by clinicians, other behavioural interventions, and partner notification.

All those elements remain but the scope of the new guidelines is much broader, with the recommendations now running to 240 pages. Whereas previous guidelines were clearly focused on the individual’s knowledge and behaviour, the new recommendations take greater account of social and structural factors as well as the profound impact that antiretrovirals have on HIV transmission. For example, an individual may need support with poverty, mental illness, substance use or unstable housing in order to be able to fully engage with medical care and adhere to HIV treatment.

Continue reading on aidsmap.com.

“Syphilis is like the canary in the coal mine for HIV”

From Queerty.com

Think twice before hooking up with that out-of-towner this holiday weekend. And, if you do, be safe.

The CDC has just released reports that number of syphilis infections in the United States jumped a whopping 10 percent from 2012 to 2013, with gay and bisexual men accounting for 75 percent of the increase.

According to the report, 17,357 cases of syphilis were reported last year. That’s 5.5 cases per every 100,000 people.

Dr. Jill Rabin, co-chief of the division of ambulatory care in the Women’s Health Programs-PCAP Services at North Shore-LIJ Health System in New Hyde Park, N.Y., called the rise in syphilis cases “very alarming.”

“Syphilis is like the canary in the coal mine for HIV,” she said. “People are going to be positive for syphilis before they are diagnosed with HIV. This means that there is a potential increase in HIV cases.”

According to MedicalXpress, the sores caused by syphilis make HIV transmission easier. In rare cases, syphilis can lead to serious health problems, including death. Though it’s easy to cure with antibiotics if caught early.

“Having an STD doesn’t mean someone is dirty or broken,” said Fred Wyand, spokesperson for the American Sexual Health Association. “Far from it.”

Wyand urged people not to let the stigma of a STD prevent them from being tested and treated.

“One of the great barriers to having sexual health conversations is the sense of embarrassment. People need to have frank, open conversations,” he said. “It’s not about sex. It’s about health.”

Syphilis on the rise among gay, bisexual men: CDC

From HealthDay.com
By Steven Reinberg

The number of cases of syphilis in the United States jumped 10 percent from 2012 to 2013, with gay and bisexual men accounting for 75 percent of the increase, U.S health officials reported Tuesday.

Rates of another sexually transmitted disease — chlamydia — fell for the first time in 30 years, with more than 1.4 million reported cases in 2013. This represented a 1.5 percent decrease from 2012, according to the U.S. Centers for Disease Control and Prevention.

“There are over 20 million cases of sexually transmitted diseases [STDs] every year in the United States, and they continue to pose a risk of lifelong complications for millions of Americans,” said Dr. Jonathan Mermin, director of CDC’s National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention.

According to the report, 17,357 cases of syphilis were reported in 2013 — a rate of 5.5 per 100,000 people.

There are a variety of reasons that put gay and bisexual men at high risk for syphilis, said Mermin.

“Some are the high number of sexual partners and sexual networks that create a vicious cycle where the prevalence of syphilis is higher. And that leads to higher incidence, which leads to higher prevalence, and that cycle can increase the frequency of infection,” he said.

Continue reading on HealthDay.

Smoking doubles risk of death for patients taking HIV therapy

From aidsmap.com

Smoking doubles the mortality risk for people with HIV taking antiretroviral therapy, a study published in AIDS shows. Smokers had an increased risk of death from cardiovascular disease (CVD) and non-AIDS-related cancers, and the life expectancy of a 35-year-old man with HIV was reduced by almost eight years due to smoking. “Smoking was associated with a two-fold increase in mortality,” comment the authors. “More than a third of all non-AIDS related malignant deaths were from lung cancer and all deaths from lung cancer were in smokers.”

The benefits of not smoking were clear. HIV-positive non-smokers who were doing well on antiretroviral therapy had a similar life expectancy to non-smokers in the general population.

With the right treatment and care, people living with HIV can have a normal life expectancy. However, mortality rates remain higher among people with HIV compared to the background population. The reasons for this are unclear, but important causes of death among people with HIV now include smoking-related diseases such as heart and lung complaints and non-AIDS-related malignancies.

Investigators therefore wanted to determine the association between smoking and mortality risk among people taking HIV therapy.

Continue reading on aidsmap.com.

Young gay men describe trust as an HIV prevention strategy

What constitutes safer sex? Sex with a condom? Sex with PrEP (pre-exposure prophylaxis)? Oral sex? At GAYCON 2014, an annual conference on gay and bisexual men’s health in Scotland, researcher Nicola Boydell presented the results of a study that sought to discern young gay men’s attitudes toward safer sex, Aidsmap reports.

The good news: Young gay men see safer sex as more than just condom use. The bad news? Many consider condomless sex within the context of a relationship as being relatively safe, even when they knew nothing about their partner’s HIV testing history.

Yet, the majority of HIV transmissions among gay men happen within the context of a relationship, according to data from a 2009 U.S. study. When speaking of these relationships, men cite trust as the number one reason to take off the condom.

Continue reading on The Body.

 

26th World AIDS Day: Get in there, do something, change things

From Huffington Post…
by

red ribbonPre-exposure prophylaxis (PrEP) and treatment as prevention (TasP) have successfully returned sexual health to the national and international headlines. Not since the early years of the HIV epidemic has there been so much constructive dialogue, progress, and involvement by the public.

Long-term survivors, HIV organizations, scientists, public-health experts, and the generation that never knew a world without HIV joined hands on the 26th World AIDS Day in an effort to educate and advocate in commemoration of those we have lost to HIV and the people living with the infection today.

While a few still wage a lonely and wasteful fight against science and progress itself, it is time to acknowledge that we finally have the opportunity to move on from a monotonous, one-way conversation and use these new tools as catalysts for serious and much-needed change.

Of course, it doesn’t help when one of our favorite Star Trek actors throws all logic overboard and simply dismisses today’s generation as lazy, complacent and irresponsible, but it certainly shows that we haven’t progressed much since President Reagan’s infamous call to abstinence 27 years ago.

Six of the estimated 39 million people we lost worldwide to HIV were my friends and mentors. All six would have agreed with Meryl Streep’s Margaret Thatcher when she says in The Iron Lady, [I]f something’s wrong, they shouldn’t just whine about it. They should get in there and do something about it. Change things.”

Keep reading on Huffington Post.